Marta Varela-Eirín
Lab alumni
- Spent 2 years and 8 months in the lab, from November 2019 through June 2022
- From Spain 🇪🇸
osteoarthritis
purinergic signaling
dietary interventions
Publications with the lab 7
Converting cell death into senescence by PARP1 inhibition improves recovery from acute oxidative injury.
2024
Nehme J,
Mesilmany L,
Varela-Eirin M,
Brandenburg S,
Altulea A,
Lin Y,
Gaya d,
Seelen M,
Hillebrands J,
van G,
Saab R,
Akl H,
Prevarskaya N,
Farfariello V,
Demaria M
Nat Aging
High dietary protein and fat contents exacerbate hepatic senescence and SASP in mice.
2023
Nehme J,
Yang D,
Altulea A,
Varela-Eirin M,
Wang L,
Hu S,
Wu Y,
Togo J,
Niu C,
Speakman J,
Demaria M
FEBS J
Cellular senescence.
2022
Varela-Eirín M,
Demaria M
Curr Biol
Pharmacological CDK4/6 inhibition reveals a p53-dependent senescent state with restricted toxicity.
2022
Wang B,
Varela-Eirin M,
Brandenburg S,
Hernandez-Segura A,
van V,
Jongbloed E,
Wilting S,
Ohtani N,
Jager A,
Demaria M
EMBO J
Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression.
2021
van V,
Varela-Eirin M,
Wang B,
Borghesan M,
Brandenburg S,
Franzin R,
Evangelou K,
Seelen M,
Gorgoulis V,
Demaria M
Mol Cell
Algorithmic assessment of cellular senescence in experimental and clinical specimens.
2021
Kohli J,
Wang B,
Brandenburg S,
Basisty N,
Evangelou K,
Varela-Eirin M,
Campisi J,
Schilling B,
Gorgoulis V,
Demaria M
Nat Protoc
A Senescence-Centric View of Aging: Implications for Longevity and Disease.
2020
Borghesan M,
Hoogaars W,
Varela-Eirin M,
Talma N,
Demaria M
Trends Cell Biol