I am a biomedical specialist from the Federal University of Pernambuco (UFPE), Brazil, my country of origin. During graduation, I conducted research in two major areas– Neuroendocrine Physiology and Population Genetics. In Physiology, I developed in vivo experiments with the objective of understanding the response of the HMGB1 protein in the Hypothalamus-Neurohypophyseal Axis in the face of sepsis situations. In the area of Genetics, I worked with the development and updating of the Database of Genetic Profiles of a State in Brazil. I am now a PhD student, in the double-degree modality at the University of Groningen and at PUCRS in Brazil, and my main topic of interest includes microglia and their relationship with aging brain. In my free time I enjoy writing, exercising, and discovering new places.
Letícya-Simone Melo Dos Santos
Lab alumni
- Spent 2 years in the lab, from August 2022 until August 2024
- From Brazil 🇧🇷
microglia
aging brain
Publications with the lab 2
Cellular senescence in brain aging and neurodegeneration.
2024
Melo D,
Trombetta-Lima M,
Eggen B,
Demaria M
Ageing Res Rev
Circulating monocytes expressing senescence-associated features are enriched in COVID-19 patients with severe disease.
2023
Lin Y,
Postma D,
Steeneken L,
Melo D,
Kirkland J,
Espindola-Netto J,
Tchkonia T,
Borghesan M,
Bouma H,
Demaria M
Aging Cell