I obtained a BSc in biomedical sciences (honors) from the University of Malaya, Malaysia; and a MSc in biomedical sciences (research) from the University of Groningen, the Netherlands. During my Master's internships, I focused on molecular biology and the diseases of old age. I did one of my Masterโs internships in Marcoโs lab, where we studied the association between dietary macronutrients and cellular senescence in mice. I started my PhD in January 2022. I am currently interested in the differences between beneficial and detrimental senescence, and identifying transcriptomic profiles for each type. I mainly deal with single cell RNA-seq datasets and bioinformatics using R language. I also work in the lab to generate my own data.
Abdullah Altulea
โ MSc
PhD student
- Joined in January 2022
- Previously in our lab: Master's student (2020)
- From Iraq ๐ฎ๐ถ
bioinformatics
(sc)RNA-seq analysis
Publications with the lab 10
Disruption of CDK4/6-RARฮฑ-NF-ฮบB axis attenuates senescence-associated inflammation and improves function during aging and following chemotherapy.
2026
Wang B,
Piccolantonio A,
Altulea A,
Huang M,
Joshi T,
Pagliarin F,
Di P,
Lin Y,
Mackedenski S,
Ustyantsev K,
Jager C,
Berezikov E,
Demaria M
Nat Aging
SenFlag gene signature identifies senescent cells in mouse and human tissues through a conserved core transcriptional program.
2026
Altulea A,
Mackedenski S,
Nehme J,
Demaria M
EMBO J
Effects of nutritional interventions on biomarkers of cellular senescence in humans: a systematic review.
2026
Lin Y,
Altulea A,
Demaria M
Ageing Res Rev
Dual role of MIF in aging and cellular senescence.
2026
Altulea A,
Nehme J,
Demaria M
Cytokine Growth Factor Rev
Pharmacological CDK4/6 inhibition promotes vulnerability to lysosomotropic agents in breast cancer.
2025
Nehme J,
Maassen S,
Bravaccini S,
Zanoni M,
Gianni C,
De G,
Soto-Gamez A,
Altulea A,
Gheorghe T,
Wang B,
Demaria M
EMBO J
Sport and longevity: an observational study of international athletes.
2024
Altulea A,
Rutten M,
Verdijk L,
Demaria M
Geroscience
Converting cell death into senescence by PARP1 inhibition improves recovery from acute oxidative injury.
2024
Nehme J,
Mesilmany L,
Varela-Eirin M,
Brandenburg S,
Altulea A,
Lin Y,
Gaya d,
Seelen M,
Hillebrands J,
van G,
Saab R,
Akl H,
Prevarskaya N,
Farfariello V,
Demaria M
Nat Aging
Decoding of translation-regulating entities reveals heterogeneous translation deficiency patterns in cellular senescence.
2023
Papaspyropoulos A,
Hazapis O,
Altulea A,
Polyzou A,
Verginis P,
Evangelou K,
Fousteri M,
Papantonis A,
Demaria M,
Gorgoulis V
Aging Cell
The effects of macronutrients metabolism on cellular and organismal aging.
2023
Nehme J,
Altulea A,
Gheorghe T,
Demaria M
Biomed J
High dietary protein and fat contents exacerbate hepatic senescence and SASP in mice.
2023
Nehme J,
Yang D,
Altulea A,
Varela-Eirin M,
Wang L,
Hu S,
Wu Y,
Togo J,
Niu C,
Speakman J,
Demaria M
FEBS J